Moltzahn et al. Serum microRNAs in prostate cancer
نویسندگان
چکیده
(1) The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, (2) Center for Reproductive Sciences, (3) Department of Urology, (4) Department of Epidemiology and Biostatistics (5) Division of Hematology and Oncology, Department of Medicine, (6) Department of Pathology and (7) UCSF – Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, (8) Roche Molecular Diagnostics, 4300 Hacienda Drive, Pleasanton, CA 94588, USA Corresponding Author: Robert Blelloch 513 Parnassus Avenue, HSE-1621, Box-0525, San Francisco, CA 94143-0525 Phone:415-476-2838, Fax:415-476-1635 [email protected] Running title: Serum microRNAs in prostate cancer
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Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients.
Recent prostate-specific antigen-based screening trials indicate an urgent need for novel and noninvasive biomarker identification strategies to improve the prediction of prostate cancer behavior. Noncoding microRNAs (miRNA) in the serum and plasma have been shown to have potential as noninvasive markers for physiologic and pathologic conditions. To identify serum miRNAs that diagnose and corre...
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